A Study on the Heterogeneity of Efficacy of Interventional Therapy Combined With Systemic Therapy for Liver Cancer Based on Multi-center Real-world Data
NCT07156617 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 2000
Last updated 2025-09-05
Summary
The system assesses the heterogeneity of HCC patients in terms of therapeutic outcomes (such as rwPFS, ORR, PRO) and adverse reactions during the process of interventional therapy combined with systemic treatment. It explores the clinical characteristics and biomarker levels of patients related to heterogeneity and builds a machine learning model to predict the risk of adverse reactions, providing evidence support for the construction of a patient-centered individualized decision-making system.
Conditions
- Hepatocellular Carcinoma (HCC)
Interventions
- PROCEDURE
-
Interventional therapy
Interventional therapy
- DRUG
-
Systemic therapy
Targeted Therapy drugs include but are not limited to Lenvatinib, Apatinib, etc. Immunotherapy drugs include but are not limited to Camrelizumab, Tislelizumab
Sponsors & Collaborators
-
Xuhua Duan
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-10-01
- Primary Completion
- 2027-10-01
- Completion
- 2028-10-01
Countries
- China
Study Locations
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