MedTrace Logo

Surgery With or Without Hepatic Arterial Chemotherapy in Treating Patients With Liver Cancer

NCT00238160 · Status: WITHDRAWN · Phase: PHASE3 · Type: INTERVENTIONAL

Last updated 2013-05-30

No results posted yet for this study

Summary

RATIONALE: Drugs used in chemotherapy, such as fluorouracil and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving drugs directly into the arteries around the tumor may kill more tumor cells. Giving chemotherapy after surgery may kill any remaining tumor cells. It is not yet known whether surgery and hepatic arterial chemotherapy are more effective than surgery alone in treating patients with liver cancer that has spread to the portal vein.

PURPOSE: This randomized phase III trial is studying surgery and hepatic arterial chemotherapy to see how well they work compared to surgery alone in treating patients with liver cancer that has spread to the portal vein.

Conditions

  • Localized Resectable Adult Primary Liver Cancer
  • Stage III Childhood Liver Cancer

Interventions

DRUG

cisplatin

DRUG

fluorouracil

PROCEDURE

adjuvant therapy

PROCEDURE

chemotherapy

PROCEDURE

conventional surgery

PROCEDURE

hepatic arterial infusion

PROCEDURE

surgery

Sponsors & Collaborators

  • Kyoto University

    lead OTHER

Principal Investigators

  • Iwao Ikai, MD · Kyoto University Hospital

Study Design

Purpose
TREATMENT

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Countries

  • Japan

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00238160 on ClinicalTrials.gov