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In Vivo Investigation of Initial Stages of Enamel Erosion

NCT02533466 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2017-08-02

Study results available
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Summary

This exploratory study is designed to help develop a clinical model to measure the earlier stages of dietary acid medicated enamel loss. The study will use fluoride as positive control to explore the validity of this design.

Conditions

  • Tooth Erosion

Interventions

OTHER

Sodium fluoride + potassium nitrate

Marketed toothpaste containing 1450ppm fluoride as sodium fluoride and 5% potassium nitrate

OTHER

Potassium nitrate

Experimental toothpaste containing 5% potassium nitrate

Sponsors & Collaborators

Principal Investigators

  • GSK Clinical Trials · GlaxoSmithKline

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-10-01
Primary Completion
2015-11-06
Completion
2015-11-06

Countries

  • United Kingdom

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02533466 on ClinicalTrials.gov