Human Plasma Fatty Acid Oscillations
NCT02502435 · Status: SUSPENDED · Type: OBSERVATIONAL · Enrollment: 12
Last updated 2026-01-23
Summary
This study wishes to look at the 24-hour rhythm of certain fats in the blood stream. Recent studies in animals and healthy participants suggest that unusual eating habits may be connected to a change in the 24-hour rhythm of the blood fats the investigators wish to measure. The investigators will ask persons suffering from night eating syndrome, a condition where people eat additional meals throughout the night, to participate in this study. Healthy volunteers who are of the same age and gender, and have a comparable body-mass-index, a number calculated from a person's weight and height, will also be asked to participate.
The aim is to learn how the 24-hour rhythm of the blood fats the investigators measure differs between the persons experiencing the night eating episodes and persons who do not.
Conditions
- Healthy
- Nocturnal Eating-Drinking Syndrome
Interventions
- OTHER
-
Observation
Observational study
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
Georgios Paschos, PhD · University of Pennsylvania
-
Kelly C Allison, PhD · University of Pennsylvania
-
Garret A FitzGerald, MD · University of Pennsylvania
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2015-07-31
- Primary Completion
- 2027-06-30
- Completion
- 2028-07-31
Countries
- United States
Study Locations
More Related Trials
-
Measurement of Lipogenic Flux by Deuterium Resolved Mass Spectrometry Via Non-invasive Breath Analysis
NCT05274334 ·Status: COMPLETED ·Phase: NA
-
Lifestyle Intervention Feasibility for Arrhythmia and Symptoms With Intermittent Fasting (LIFE AS IF)
NCT04090840 ·Status: COMPLETED ·Phase: NA
-
The Fasting Study - Unraveling the Mechanistic Effects of Prolonged Fasting in Humans.
NCT03757767 ·Status: COMPLETED ·Phase: NA
-
Effect of Obesity-derived Cytokines on Protein Turnover and Carbohydrate Metabolism in Human Skeletal Muscle
NCT02305069 ·Status: COMPLETED ·Phase: NA
-
Diurnal Variability in the Regulation of Beta-cell Function and Insulin Sensitivity in Overweight People
NCT02011581 ·Status: COMPLETED
-
Prolonged Overnight Fast, Energy Metabolism and Skeletal Muscle Anabolic Sensitivity
NCT05420181 ·Status: COMPLETED ·Phase: NA
-
Comparison of the Short-Term Effect of Dietary Carbohydrate Restriction Versus Exogenous Ketone Supplementation on Myocardial Glucose Suppression and Timing to Achieve a State of Ketosis Using FDG PET/CT Serial Imaging
NCT04275453 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Tissue Lipids and Insulin Resistance
NCT00483210 ·Status: WITHDRAWN ·Phase: NA
-
Food Rheology and Feeding in Lean and Obese Humans
NCT00260130 ·Status: COMPLETED ·Phase: NA
-
Relationship Between Systemic Fatty Acid Availability and Insulin Sensitivity
NCT01452048 ·Status: COMPLETED
-
Prolonged Daily Fasting as a Viable Alternative to Caloric Restriction in At-Risk Obese Humans
NCT04259632 ·Status: COMPLETED ·Phase: NA
-
Fat Effects in Women With Metabolic Syndrome
NCT01093560 ·Status: UNKNOWN ·Phase: NA
-
Effects of Diet Changes on Metabolism
NCT00523627 ·Status: COMPLETED
-
A Short Term Evaluation of a Structured Weight Loss Plan in Overweight and Obese Adults
NCT02774668 ·Status: COMPLETED ·Phase: NA
-
Impact of Exercise on the Metabolic Consequences of Overeating
NCT02701738 ·Status: COMPLETED ·Phase: NA
-
The Effects of Increasing Caloric Intake on Diet-Induced Thermogenesis and 24h Energy Expenditure
NCT05545306 ·Status: RECRUITING ·Phase: NA
-
Effect of Late Dinner on Nocturnal Metabolism
NCT03525717 ·Status: COMPLETED ·Phase: NA
-
The Effects of Gastric or Duodenal Nutrient Infusion on Food Intake, Obesity and Comorbidities in Obese Individuals
NCT02880813 ·Status: COMPLETED ·Phase: NA
-
Fatty Acid Oxidation Defects and Insulin Sensitivity
NCT02517307 ·Status: COMPLETED ·Phase: NA
-
Postprandial Fatty Acid Metabolism in the Natural History of Type 2 Diabetes (T2D)
NCT02808182 ·Status: COMPLETED ·Phase: NA
-
Postprandial Profiles of Metabolites and Appetite-regulating Hormones in Plasma and Cerebrospinal Fluid
NCT06115304 ·Status: RECRUITING ·Phase: NA
-
Effects of Fasting and Exercise on Insulin and GH Signaltransduction in Muscle and Fat
NCT00817440 ·Status: COMPLETED ·Phase: NA
-
Effect of Increased Free Fatty Acids on Leptin Function
NCT01520454 ·Status: COMPLETED ·Phase: NA
-
Impact of a High Saturated Fat Diet on Fasted Systemic and White Adipose Tissue Inflammatory Responses
NCT03569189 ·Status: COMPLETED ·Phase: NA
-
The Effects of Sodium Phenylbutyrate on Circulating Branched Chain Amino Acids
NCT05028803 ·Status: COMPLETED ·Phase: NA