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The Effects of Sodium Phenylbutyrate on Circulating Branched Chain Amino Acids

NCT05028803 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 8

Last updated 2026-04-28

No results posted yet for this study

Summary

The aim of this study is to reduce fasting circulating BCAA concentrations in volunteers using Sodium Phenylbutyrate. In addition, we aim investigate the effect of BCAA lowering on fasting blood glucose levels, insulin sensitivity measures and muscle metabolism.

Conditions

  • Obese Non Diabetic

Interventions

DRUG

sodium phenylbutyrate

same as arm/group

Sponsors & Collaborators

  • University of Nottingham

    lead OTHER

Principal Investigators

  • Philip Prof Athertone, DM · University of Nottingham

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-09-01
Primary Completion
2023-09-01
Completion
2024-03-01

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05028803 on ClinicalTrials.gov