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Assessment of Voluntary and Reflex Cough in Patients With ALS

NCT02495571 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2015-10-14

No results posted yet for this study

Summary

This study aims to assess the presence and the intensity of voluntary and cough reflex in patients with amyotrophic lateral sclerosis (ALS), comparing the results with the healthy control group. The assessment of the cough is fundamental to verify the mechanism of airways protection which is particularly compromised in ALS patients.

Objective parameters of voluntary and reflex cough would be measured by the spirometer. The reflex of cough would be elicited by a solution of citric acid through an ultrasonic nebulizer.

Conditions

Interventions

OTHER

Cough Assessment in ALS Patients

1. Volitional Cough assessment by spirometer: a) Peak Cough Espiratory Flow (PCEF) 2. Cough Reflex Test a) Peak Cough Espiratory Flow (PCEF)

Sponsors & Collaborators

  • IRCCS San Camillo, Venezia, Italy

    lead OTHER

Principal Investigators

  • IRENE BATTEL · IRCCS San Camillo, Venezia, Italy

Study Design

Allocation
NON_RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-10-31
Primary Completion
2015-10-31
Completion
2016-06-30

Countries

  • Italy

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02495571 on ClinicalTrials.gov