Instrumental and Manual Increase of Couch in Neuromuscular Patients

Summary

Inefficient cough is responsible of respiratory complications in neuromuscular patients which can lead to hospitalisation and can be life threatening. Techniques enhancing cough efficiency are successful in improving the clearance of bronchial secretions and help non invasive ventilation efficiency especially in case of acute respiratory failure. Combining mechanical exsufflation to the manual techniques of physiotherapy might enhance efficiency. Therefore the investigators want to compare cough efficiency under different techniques of instrumental and manual of cough assistance in order to determine the best combination to optimize cough flow.

Conditions

• Neuromuscular Disease
• Chronic Respiratory Failure
• Coughing

Interventions

DEVICE

Alpha 200®

inspiratory capacity is increased with the use of constant pressure device: Alpha 200®

DEVICE

Alpha 200® + physiotherapist

inspiratory capacity is increased with the use of constant pressure device (Alpha 200®) combined with the manual pressures techniques to increase cough by the physiotherapist

DEVICE

Cough Assist®

increased inspiratory capacity and mechanical exsufflation with the use of insufflation-exsufflation device (Cough Assist®)

DEVICE

Cough Assist® + physiotherapist

increased inspiratory capacity and mechanical exsufflation with the use of insufflation-exsufflation device (Cough Assist®) combined with the manual pressures techniques to increase cough by the physiotherapist

OTHER

physiotherapist

manual pressures techniques to increase cough applied by the physiotherapist

Sponsors & Collaborators

• Adep Assistance

  collaborator OTHER

• Centre d'Investigation Clinique et Technologique 805

  lead OTHER

Principal Investigators

• Frederic Lofaso, Md-PhD · University of Versailles

• Helene Prigent, MD-PhD · University of Versailles

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

SINGLE_GROUP

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2012-01-31

Primary Completion

2012-01-31

Completion

2013-07-31

Countries

• France

Study Locations