Symptoms of Lower Urinary Tract Dysfunction Phenotyping Study

Summary

The purpose of this study is to advance our understanding of people who experience urinary and bladder problems. We are interested in learning about people's experiences with urinary symptoms and how these symptoms will be managed. We want to understand the important differences among people and what factors affect urinary and bladder problems. After all of the information is collected, we will have a better understanding of how to improve the care and treatment for people who have urinary and bladder problems.

Conditions

• Lower Urinary Tract Symptoms

Interventions

OTHER

None-observational

For surgical patients, follow-up assessments will occur 3 and 12 months after the surgery. For medical patients, follow-up assessments will occur 3 and 12 months after the baseline assessment.

PROCEDURE

Magnetic Resonance Imaging (MRI)

One time MRI scanning session examining brain structure and function in a resting state and after water consumption.

OTHER

Multimodal Automated Sensory Testing System

Pressure pain thresholds will be assess using computer-controlled pressures delivered by a device called the Multimodal Automated Sensory Testing System (MAST) device on to the subjects thumbnail bed.

OTHER

Auditory Sensitivity Test

Subjects' sensitivity to sound will be evaluated using a series of sounds delivered by a standard audiometer device.

Sponsors & Collaborators

• National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

  collaborator NIH

• University of Michigan

  collaborator OTHER

• Northwestern University

  collaborator OTHER

• Duke University

  collaborator OTHER

• University of Iowa

  collaborator OTHER

• University of Washington

  collaborator OTHER

• Washington University School of Medicine

  collaborator OTHER

• Arbor Research Collaborative for Health

  lead OTHER

Principal Investigators

• Kevin P Weinfurt, PhD · Duke University

• Claire Yang, MD · University of Washington

• Robert M Merion, MD, FACS · Arbor Research Collaborative for Health - DCC

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2015-04-30

Primary Completion

2018-04-30

Completion

2018-05-31

Countries

• United States

Study Locations