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Brain Lesions in Relation to Motor Profiles of Children With Cerebral Visual Impairment.

NCT02480452 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 600

Last updated 2023-01-27

No results posted yet for this study

Summary

The overall goal of this research proposal is the early prediction of the emergence of CVI and its characteristics on the basis of neuroimaging data.

The different steps that will be taken to achieve this goal will be:

1. To characterize CVI deficits in children;
2. To correlate the CVI characteristics with their motor profiles;
3. To characterize brain lesions in children with CVI;
4. To link the motor profile, CVI profile and brain metrics of the children.

Over the last 10 years, 488 children with and without CP have consulted at the CVI clinic in Leuven. All these children had a comprehensive visual perceptual assessment, cognitive evaluation and an ophthalmological assessment. Summarizing these data results in a quantitative visual perceptual profile for each individual patient. The goal is to prospectively extend this database to a number of 600 children. The project's primary objective is to relate the presence of CVI to the motor profiles of these children.

Of these 488 children, 300 have an MRI available. The goal is to analyze the retrospective MRI data of this clinical group and to prospectively extend this database by reassuring newly registered children will receive MRI with DTI. This will allow the investigation of the correlation between the brain metrics and the CVI characteristics in a large cohort.

Conditions

  • Visual Pathway Diseases; Neuroimaging

Sponsors & Collaborators

  • Universitaire Ziekenhuizen KU Leuven

    lead OTHER

Eligibility

Min Age
3 Years
Max Age
6 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-05-31
Primary Completion
2018-06-30
Completion
2019-06-30

Countries

  • Belgium

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02480452 on ClinicalTrials.gov