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Acute Dietary Nitrate in Dilated Cardiomyopathy

NCT02471417 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 12

Last updated 2015-06-15

No results posted yet for this study

Summary

Acute consumption of dietary nitrate (as beetroot juice) has been shown to improve exercise capacity in athletes, healthy adults and subjects with both peripheral vascular disease or COPD. Many patients with dilated cardiomyopathy have reduced exercise capacity, The investigators hypothesized that acute nitrate consumption might increase incremental shuttle walk test (ISWT) distance in dilated cardiomyopathy subjects compared to a placebo beetroot juice.

Conditions

Interventions

DIETARY_SUPPLEMENT

Dietary nitrate

140ml of nitrate rich beetroot juice provides 12.9mmol nitrate and will be on a single occasion by the study subjects.

DIETARY_SUPPLEMENT

Placebo

140ml of nitrate depleted beetroot juice provides 0.5mmol nitrate and will be on a single occasion by the study subjects.

Sponsors & Collaborators

  • University College Dublin

    collaborator OTHER

  • Connolly Hospital Blanchardstown

    collaborator OTHER

  • Royal College of Surgeons, Ireland

    lead OTHER

Principal Investigators

  • Jim O 'Neill, MD · Connolly Hospital Blanchardstown

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Sex
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-01-31
Primary Completion
2015-05-31
Completion
2015-05-31

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02471417 on ClinicalTrials.gov