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Laboratory Evaluation of Pregnancy Malaria Vaccine Candidates/In-vitro Testing of Pregnancy Malaria Vaccine Candidates

NCT02471378 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 7476

Last updated 2026-05-18

No results posted yet for this study

Summary

Background:

\- Malaria is a disease that affects many people in African countries. It is caused by germs that are spread by mosquito bites. It can be fatal if not diagnosed and treated right away. Children younger than 5 and pregnant women are most at risk to get malaria. Researchers want to create a vaccine that will prevent malaria infection during pregnancy.

Objectives:

\- To create a vaccine that will prevent malaria infection during pregnancy. To assess possible vaccines using in-vitro tests with parasites taken from pregnant women.

Eligibility:

\- Pregnant women ages 15-25

Design:

* The study site is an area in Mali, West Africa.
* Participants:
* Will have blood drawn.
* Will give consent for the blood sample to be used for future research.
* May have a physical exam.
* Participants who have malaria or anemia will get treatment.

Conditions

Sponsors & Collaborators

  • National Institute of Allergy and Infectious Diseases (NIAID)

    lead NIH

Principal Investigators

  • Michal Fried, Ph.D. · National Institute of Allergy and Infectious Diseases (NIAID)

Eligibility

Min Age
15 Years
Max Age
25 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-07-28
Primary Completion
2026-06-30
Completion
2028-06-30

Countries

  • Mali

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02471378 on ClinicalTrials.gov