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Study of Venous Endothelial Cells in Rheumatoid Arthritis

NCT02468986 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 56

Last updated 2021-04-02

No results posted yet for this study

Summary

Heart disease is the major contributor of early death in rheumatoid arthritis (RA) and is not influenced by traditional risk factors. Blood vessel dysfunction has been associated with heart disease and complications such as heart attack. The vessel dysfunction is thought to be mediated in part to inflammation. RA patients have evidence of vessel dysfunction seen on ultrasound that improves after medications are given.

The purpose of this study is to evaluate patients with controlled or uncontrolled rheumatoid arthritis to determine if there is a difference in the protein expression in the cells that line the blood vessels compared to healthy people.

Conditions

Sponsors & Collaborators

Principal Investigators

  • Elizabeth B Solow, MD · University of Texas

  • David Karp, MD, PhD · University of Texas

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-08-31
Primary Completion
2019-08-31
Completion
2020-12-31

Countries

  • United States

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02468986 on ClinicalTrials.gov