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Intraoperational Prostate Loge Biopsies (iPROLOGX) After Radical Prostatovesiculectomy

NCT02460861 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 279

Last updated 2015-06-03

No results posted yet for this study

Summary

This project is about the detection of occult tumor cells in surgical margins of radical prostatovesiculectomy by analysing the methylation status of Glutathione S-transferase P 1 (GSTP1). After gland excision specimens are obtained from 9 defined areas of the prostatic fossa. The biopsies are divided into two parts. One part used for histopathological analysis and the other part for moleculargenetic analysis. Results will be correlated e.g. with tumor stage, Gleason Score and prostate specific antigen (PSA).

The prostate-cancer-negative control group with bladder cancer.

Conditions

Interventions

PROCEDURE

biopsies of the prostatic fossa in Magdeburg

intraoperative Open surgical biopsies of the prostatic fossa after prostatevesiculectomy in Magdeburg

PROCEDURE

RPVE

Open Radical prostatovesiculectomy in Magdeburg

PROCEDURE

ETRARP

Robotassisted Radical prostatovesiculectomy in Gronau

PROCEDURE

CE

Open cystectomy in Magdeburg/Gronau

PROCEDURE

biopsies of the prostatic fossa in gronau

intraoperative endoscopic robotassisted biopsies of the prostatic fossa after prostatevesiculectomy in Gronau

Sponsors & Collaborators

  • St. Antonius Hospital Gronau

    collaborator OTHER

  • University of Magdeburg

    lead OTHER

Principal Investigators

  • Martin Schostak, Prof.Dr.med. · University of Magdeburg

Study Design

Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-11-30
Primary Completion
2013-10-31
Completion
2015-12-31

Countries

  • Germany

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02460861 on ClinicalTrials.gov