Study of Methodologies to Measure Blood Flow and Oxygenation in Adults With Sickle Cell Disease
NCT02447627 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 38
Last updated 2020-12-19
Summary
The purpose of the study is to determine whether imaging techniques, such as magnetic resonance imaging (MRI), near infrared spectroscopy (NIRS), laser speckle contrast imaging (LSCI), and optical imaging (OI), can detect differences in blood flow and oxygen levels in different organ systems of participants with sickle cell disease (SCD). Differences in blood flow and oxygen levels detected by these techniques will be evaluated to determine their utility as biomarkers of clinical disease pathophysiology.
Conditions
- Healthy
- Sickle Cell Disease
Sponsors & Collaborators
-
Bioverativ Therapeutics Inc.
lead INDUSTRY
Principal Investigators
-
Medical Director · Bioverativ Therapeutics Inc.
Eligibility
- Min Age
- 18 Years
- Max Age
- 45 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2015-06-30
- Primary Completion
- 2016-10-31
- Completion
- 2016-10-31
Countries
- United States
Study Locations
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