Diclofenac Premedication, as the Effect of Preemptive Analgesia After Post-thoracotomy Chest and Shoulder Pain

Summary

The purpose of the study is to examine if the hyposthesis of the preventive analgestic characteristic of diclofenac given preoperatively has any effect on postoperative thoracic wall and shoulder pain sensation. We also want to examine the rescue analgetic consumption and the postoperative lung function test values.

Conditions

• Pain
• Inadequate or Impaired Respiratory Function

Interventions

DRUG

Diclofenac

Orally 100 mg Diclofenac, administered 1 hour before surgery

DRUG

Midazolam

5 mg Dormicum intramuscularly, administered 1 hour before surgery

DRUG

Atropine

0.5 mg Atropine intramuscularly, administered 1 hour before surgery

DRUG

bucain + fentanyl

Via the thocacic epidural cannula 1mg/ml bucain + 5microgr/ml fentanyl solution, with 0.1ml/kg body mass/hour speed is administered.

DRUG

Nalbuphine

1st choice for rescue analgetic 10-20 mg intravenously

DRUG

Diclofenac

2nd choice for rescue analgetic 250ml intravenously

DRUG

Metamizole-sodium

Additional rescue analgetic 2g intravenously

DRUG

Tramadol

Additional rescue analgetic 100mg intravenously

Sponsors & Collaborators

• University of Debrecen

  lead OTHER

Principal Investigators

• Béla Fülesdi, MD,PhD,DSci · UNIVERSITY OF DEBRECEN FACULTY OF MEDICINE Department of Anesthesiology and Intensive Care Debrecen, Hungary, 4032

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Model

CROSSOVER

Eligibility

Min Age

18 Years

Max Age

80 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2014-04-30

Primary Completion

2016-04-30

Completion

2016-04-30

Countries

• Hungary

Study Locations