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High-selenium Lentils Versus Arsenic Toxicity

NCT02429921 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 400

Last updated 2017-03-31

No results posted yet for this study

Summary

About 45 million people in Bangladesh are chronically exposed to unacceptable levels of arsenic in their drinking water. Chronic arsenic poisoning leads to cancers, and vascular diseases.

This dietary trial intends to test the potential of high-selenium lentils, consumed as lentil soup, in reducing the arsenic body burden in an exposed Bangladeshi population, and in improving the overall health status.

Arsenic-exposed families will be assigned to one of two groups. One group will eat lentils (50g/person/day) that are naturally high in selenium, the other group will receive lentils with low selenium content. This 6 months trial is randomized and double-blinded.

Conditions

  • Arsenic Poisoning

Interventions

DIETARY_SUPPLEMENT

high-selenium lentils

lentils grown on naturally selenium-rich soils in the Canadian Prairies

DIETARY_SUPPLEMENT

Low-Se lentils

lentils grown on selenium-deficient soils in Idaho, USA.

Sponsors & Collaborators

  • International Centre for Diarrhoeal Disease Research, Bangladesh

    collaborator OTHER

  • University of Calgary

    lead OTHER

Principal Investigators

  • Judit EG Smits, DVM, PhD · University of Calgary, Calgary, Alberta, Canada

  • Albert Vandenberg, PhD · University of Saskatchewan

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
14 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-10-31
Primary Completion
2016-09-30
Completion
2016-09-30

Countries

  • Bangladesh

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02429921 on ClinicalTrials.gov