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Trial of Vitamin D3 Supplementation in Paediatric Asthma

NCT02428322 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 53

Last updated 2015-12-03

No results posted yet for this study

Summary

Epidemiological and observational studies have linked vitamin D deficiency with increased asthma/allergy incidence . Vitamin D insufficiency (\<75nmol/L) has been associated with increased incidence of severe childhood asthma. Further, high 25(OH)D levels were associated with reduced risk of recent hospitalization, lower use of anti-asthmatic medication and lower airway hyper-responsiveness in childhood asthmatics. The association between vitamin D and allergy and asthma appears to be stronger in children than adults, with some even suggesting that childhood asthma may may be caused by VDD.

Conditions

Interventions

DIETARY_SUPPLEMENT

Placebo

Soft gel capsules will be identical to the vitamin D intervention but contain no vitamin D.

DIETARY_SUPPLEMENT

VItamin D3

Soft gel capsules will contain 2,000IU vitamin D.

Sponsors & Collaborators

  • Conor Kerley

    lead OTHER

Principal Investigators

  • Basil Elnazir, MD · National Children's Hospital, Dublin 24, Ireland

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
6 Years
Max Age
16 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-10-31
Primary Completion
2014-05-31
Completion
2014-05-31

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02428322 on ClinicalTrials.gov