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Dry Eye Treatment With Artificial Tears

NCT02420834 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2019-01-10

No results posted yet for this study

Summary

Dry eye is a chronic irritating eye condition that affects many people, caused by poor tear quality and insufficient quantity. Treatments are traditionally in the form of artificial tears applied to the ocular surface. However, there is little evidence in the scientific literature that demonstrates their efficacy relative compared to each other, nor how to decide which one might be most effective for an individual patient. Therefore the investigators aim to examine the efficacy of different classes of artificial tears (those designed to increase viscosity, reduce evaporation or to mimic the component balance of the natural tears). In addition, the investigators also aim to determine how the treatment preferred by an individual could potentially have been predicted from their baseline condition.

Conditions

  • Dry Eye

Interventions

OTHER

Hypromellose 0.15%

Tear supplement to be taken as required to relieve symptoms

OTHER

Hypromellose 0.4%

Tear supplement to be taken as required to relieve symptoms

OTHER

Carboxymethylcellulose

Tear supplement to be taken as required to relieve symptoms

OTHER

Liposomal Spray

Tear supplement o be taken as required to relieve symptoms

Sponsors & Collaborators

  • Aston University

    lead OTHER

Principal Investigators

  • James S Wolffsohn, BSc PhD · Aston University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-04-30
Primary Completion
2019-01-31
Completion
2019-01-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02420834 on ClinicalTrials.gov