The Hasselt APPendicitis Immunology and Environmental Cohort STudy

NCT02391675 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 308

Last updated 2018-05-22

No results posted yet for this study

Summary

The Hasselt Appendicitis Immunology and Environmental Study (HAPPIEST) aims at characterizing factors that influence the development and severity of acute appendicitis. In a cohort of 300 patients and 300 controls, environmental factors as well as genetic make-up of the innate immune system, focusing mainly on pattern recognition, will be analyzed in order to gain insight in their relative importance in the pathology of appendicitis. Furthermore, populations of micro-organisms present in the gut of patients will be characterized, and the interaction between relevant micro-organisms and the innate immune system will be analyzed.

Conditions

  • Appendicitis

Sponsors & Collaborators

  • Radboud University Medical Center

    collaborator OTHER
  • Jessa Hospital

    collaborator OTHER
  • Hasselt University

    lead OTHER

Principal Investigators

  • Inge C Gyssens, MD PhD · Hasselt University

Eligibility

Min Age
5 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-06-30
Primary Completion
2018-10-31
Completion
2018-10-31

Countries

  • Belgium
  • Netherlands

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02391675 on ClinicalTrials.gov