The Hasselt APPendicitis Immunology and Environmental Cohort STudy
NCT02391675 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 308
Last updated 2018-05-22
Summary
The Hasselt Appendicitis Immunology and Environmental Study (HAPPIEST) aims at characterizing factors that influence the development and severity of acute appendicitis. In a cohort of 300 patients and 300 controls, environmental factors as well as genetic make-up of the innate immune system, focusing mainly on pattern recognition, will be analyzed in order to gain insight in their relative importance in the pathology of appendicitis. Furthermore, populations of micro-organisms present in the gut of patients will be characterized, and the interaction between relevant micro-organisms and the innate immune system will be analyzed.
Conditions
- Appendicitis
Sponsors & Collaborators
-
Radboud University Medical Center
collaborator OTHER -
Jessa Hospital
collaborator OTHER -
Hasselt University
lead OTHER
Principal Investigators
-
Inge C Gyssens, MD PhD · Hasselt University
Eligibility
- Min Age
- 5 Years
- Max Age
- 85 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2012-06-30
- Primary Completion
- 2018-10-31
- Completion
- 2018-10-31
Countries
- Belgium
- Netherlands
Study Locations
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