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Anti-Angiotensin-Receptor 1 (ATR1)-, Anti-Endothelin-Receptor A (ETRA)-Antibodies and T Cells in Cardiomyopathy

NCT02319590 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 80

Last updated 2021-07-15

No results posted yet for this study

Summary

The study aims 1) to determine autoantibody titers against the AGTR1 receptor and against the ETA receptor, 2) to characterize cytokine expression profiles of heart-specific activated T cells in patients with systolic heart failure. Auto-antibody titers and specific cytokine expression profiles in heart-specific activated T cells will then be correlated with heart failure progression and outcome.

Conditions

  • Cardiac Failure

Sponsors & Collaborators

  • Zurich Regional Health Center

    lead OTHER

Principal Investigators

  • Urs Eriksson, MD · GZO Regional Health Center and University of Zurich

Eligibility

Min Age
18 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-12-31
Primary Completion
2019-12-31
Completion
2020-12-31

Countries

  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02319590 on ClinicalTrials.gov