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Markers and Response to Cardiac Resynchronization Therapy

NCT01519908 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 240

Last updated 2024-04-18

No results posted yet for this study

Summary

The purpose of this study is to investigate: the relation of a set of (bio)markers and response to Cardiac Resynchronization Therapy (CRT); the interrelationship as well as the potential predictive power of these (bio)markers on improvement and/or deterioration of cardiac function, cardiac geometry (reverse re-modeling during CRT) will be evaluated.

(Bio)markers include but are not limited to: collagen, genomic markers, molecular markers, electrocardiographic markers, echocardiographic markers, arrhythmogenic markers and markers for renal function: blood urea nitrogen (BUN), serum creatinine, glomerular filtration rate (GFR).

Conditions

Interventions

DEVICE

CRT-D (Medtronic)

Biventricular implantable cardioverter defibrillator, post marketing release

Sponsors & Collaborators

  • Center for Translational Molecular Medicine

    collaborator OTHER

  • Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

    collaborator OTHER

  • UMC Utrecht

    collaborator OTHER

  • Maastricht University Medical Center

    collaborator OTHER

  • Free University Medical Center

    collaborator OTHER

  • University Medical Center Groningen

    lead OTHER

Principal Investigators

  • Marc Vos, MD, PhD · UMC Utrecht

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-02-29
Primary Completion
2014-12-31
Completion
2014-12-31

Countries

  • Netherlands

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01519908 on ClinicalTrials.gov