Intranasal Ketamine for Late-Life Depression and Suicidal Ideation
NCT02295787 · Status: WITHDRAWN · Phase: PHASE4 · Type: INTERVENTIONAL
Last updated 2017-03-03
Summary
The investigators of this study plan to investigate the feasibility and efficacy of repeated doses of intranasal ketamine in severely depressed patients who are at least 65 years of age and experiencing suicidal ideation. The results of the study could lead to development of new strategies for treating depression.
Conditions
- Depression
- Suicide
- Suicidal Ideation
Interventions
Sponsors & Collaborators
-
Massachusetts General Hospital
lead OTHER
Principal Investigators
-
Dawn F Ionescu, MD · Massachusetts General Hospital
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- QUADRUPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2015-07-31
- Primary Completion
- 2015-07-31
- Completion
- 2015-07-31
More Related Trials
-
A Study of SLS-002 (Intranasal Racemic Ketamine) in Adults With Major Depressive Disorder at Imminent Risk of Suicide
NCT04669665 ·Status: COMPLETED ·Phase: PHASE2
-
Ketamine Versus Placebo for Treatment Resistant Major Depressive Disorder
NCT01667926 ·Status: COMPLETED ·Phase: NA
-
Ketamine Infusion for Treatment-resistant Major Depressive Disorder
NCT01582945 ·Status: COMPLETED ·Phase: NA
-
Integrating Ketamine Effects on Neuronal Molecular Signatures and the Brain Functional and Structural Connectome
NCT06698848 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Intranasal Ketamine in Treatment-Resistant Depression
NCT01304147 ·Status: COMPLETED ·Phase: NA
-
Ketamine for Mood Disorders With Suicidal Ideation
NCT04099771 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
Treatment of Suicidal Ideation With Intravenous Ketamine Infusion
NCT01887990 ·Status: COMPLETED ·Phase: NA
-
Understanding and Treating Suicidal Ideation With Ketamine
NCT06891300 ·Status: RECRUITING ·Phase: PHASE2/PHASE3
-
A Single Ketamine Infusion Combined With Music for Suicidal Ideation
NCT04658420 ·Status: UNKNOWN ·Phase: PHASE2
-
Using a Low Dose of Ketamine vs. Active Placebo in Treating Severe Depression and Suicide
NCT03666390 ·Status: UNKNOWN ·Phase: NA
-
Study of Depression-Ketamine-Brain Function
NCT01135758 ·Status: TERMINATED ·Phase: PHASE2
-
A Study of Ketamine in Patients With Treatment-resistant Depression
NCT01627782 ·Status: COMPLETED ·Phase: PHASE2
-
Ketamine for Depression and Suicide Risk
NCT02094898 ·Status: COMPLETED ·Phase: PHASE2
-
Ketamine + Cognitive Training for Suicidality in the Medical Setting
NCT04578938 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE4
-
Understanding the Role of the Kappa Opioid Receptor in Ketamine's Attenuation of Suicidal Thoughts
NCT07139106 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
Role Of Ketamine in Treatment-Resistant Major Depressive Disorder And Its Effect on Suicidality
NCT04101474 ·Status: COMPLETED ·Phase: NA
-
Effects of Intranasal Ketamine on Depression and Anxiety in Palliative Care Cancer Patients
NCT06665568 ·Status: NOT_YET_RECRUITING ·Phase: EARLY_PHASE1
-
Ketamine in the Treatment of Depression
NCT01558063 ·Status: COMPLETED ·Phase: PHASE2
-
Long-Term Maintenance With Ketamine and Esketamine for Reduction of Suicide in High-Risk Patients With Depression
NCT05450432 ·Status: RECRUITING ·Phase: PHASE4
-
Nebulized Ketamine for the Treatment of Major Depressive Disorder
NCT06752759 ·Status: RECRUITING ·Phase: PHASE3
-
Administration of Subanesthetic Dose of Ketamine and Electroconvulsive Treatment for Treatment Resistant Depression
NCT02522377 ·Status: COMPLETED ·Phase: NA
-
Low-dose Ketamine Infusion Among Adolescents With Treatment-resistant Depression
NCT05045378 ·Status: COMPLETED ·Phase: PHASE4
-
Ketamine for Treatment Resistant Late-Life Depression
NCT02556606 ·Status: COMPLETED ·Phase: PHASE3
-
Sustained Ketamine Effectiveness for Suicidal Ideation
NCT06806475 ·Status: COMPLETED
-
Effects of Ketamine in the Acute Phase of Suicidal Ideation
NCT02299440 ·Status: COMPLETED ·Phase: PHASE3