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Role of the Peritoneal Microenvironment in the Pathogenesis and Spread of Colorectal Carcinomatosis

NCT03777943 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 53

Last updated 2024-09-19

No results posted yet for this study

Summary

The goal of this project is to investigate the extent and role of mesothelial - mesenchymal transition (MMT) and cancer associated fibroblasts (CAFs) in the pathogenesis of colorectal peritoneal carcinomatosis (PC).

Conditions

  • Peritoneal Carcinomatosis

Interventions

PROCEDURE

Sampling peritoneal tissue

Resection specimen will be obtained during CRS from normal peritoneum at a distance, normal peritoneum close to a peritoneal metastasis, miliary peritoneal carcinomatosis, and established peritoneal carcinomatosis.

Sponsors & Collaborators

  • University Ghent

    collaborator OTHER

  • Belgian Federation Against Cancer

    collaborator OTHER

  • University Hospital, Ghent

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-11-01
Primary Completion
2022-03-28
Completion
2022-03-28

Countries

  • Belgium

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03777943 on ClinicalTrials.gov