MedTrace Logo

An Investigation of the Dose-dependent Vascualr Effects of (-)-Epicatechin in Healthy Men

NCT02292342 · Status: COMPLETED · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 21

Last updated 2016-05-30

No results posted yet for this study

Summary

Aim: To investigate the dose-dependent vascular effect (primarily using FMD) of 3 low-level doses of pure (-)-epicatechin ≤ 1 mg/kg BW (0.1, 0.5 \& 1.0 mg/kg BW) in healthy men.

Conditions

  • Vasodilation

Interventions

DIETARY_SUPPLEMENT

Water

Control

DIETARY_SUPPLEMENT

Epicatechin 0.1 mg/kg

EC 0.1 mg/kg

DIETARY_SUPPLEMENT

Epicatechin 0.5 mg/kg

EC 0.5

DIETARY_SUPPLEMENT

Epicatechin 1.0 mg/kg

EC 1.0

Sponsors & Collaborators

  • University of Reading

    lead OTHER

Principal Investigators

  • Jeremy Spencer, PhD · University of Reading

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-05-31
Primary Completion
2016-02-29
Completion
2016-05-31

Countries

  • United Kingdom

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02292342 on ClinicalTrials.gov