Day-Night Rhythm in Human Skeletal Muscle
NCT02261168 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 12
Last updated 2015-09-07
Summary
This study evaluates the existence of a day-night rhythm in skeletal muscle energy metabolism in healthy lean subjects. Subjects will stay at the research facility for 44 hours with a standardized living protocol during which several measurements of skeletal muscle and whole body energy metabolism will be performed.
Conditions
- Diabetes Mellitus, Type 2
- Insulin Resistance
Interventions
- OTHER
-
Standardized living protocol
Subjects stay at the research facility for 44 hours and adhere to a standard sleeping, eating and activity protocol. During this protocol, multiple measurements will be performed including skeletal muscle biopsies (m. vastus lateralis), blood draws, indirect calorimetry and MRS measurements.
Sponsors & Collaborators
-
Maastricht University Medical Center
lead OTHER
Principal Investigators
-
Patrick Schrauwen, PhD · Professor
Study Design
- Allocation
- NA
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 35 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2014-11-30
- Primary Completion
- 2015-07-31
- Completion
- 2015-07-31
Countries
- Netherlands
Study Locations
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