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Correlation of Molecular Markers With Response to Therapy and Breast Cancer Behavior

NCT01000883 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 10000

Last updated 2025-06-18

No results posted yet for this study

Summary

RATIONALE: Studying samples of tumor tissue and blood from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors predict how patients will respond to treatment.

PURPOSE: This research study is looking at tissue and blood samples from women with locally advanced or metastatic breast cancer

Conditions

Interventions

OTHER

biologic sample preservation procedure

approximately 16-20 milligrams of tumor tissue per core will be obtained for research purposes.

OTHER

laboratory biomarker analysis

Evaluation of biomarkers will occur as questions are asked in subsequent correlative studies.

PROCEDURE

biopsy

cancer tissue will be taken from the primary breast cancer site as well as the metastatic tumor sites. Two tubes of whole blood will also be collected.

Sponsors & Collaborators

  • National Cancer Institute (NCI)

    collaborator NIH

  • UNC Lineberger Comprehensive Cancer Center

    lead OTHER

Principal Investigators

  • Lisa A. Carey, MD · UNC Lineberger Comprehensive Cancer Center

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
1998-12-01
Primary Completion
2030-11-30
Completion
2032-11-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01000883 on ClinicalTrials.gov