Assessing Parathyroid Glands Vascularisation by ICG Fluoroscopy

Summary

Evaluate parathyroid gland perfusion during total thyroidectomy or thyroid totalisation surgery. Create an objective basis for the decision whether or not to transplant the parathyroid glands. Avoide postoperative serum calcium and parathyroid hormone dosages, and thus abstention of systematic supplementation with calcium and vitamin D in case of good perfusion.

Conditions

• Parathyroid Function Low Adverse Event

Interventions

PROCEDURE

Postoperative parathyroid function test

Calcium and parathormone dosage at 24 hours and ten day after surgery

PROCEDURE

No postoperative parathyroid dosage and supplementation

The patients will be clinically followed for 24 hours after surgery and caclium and parathormone dosage will be done at ten days after surgery. No supplementation will be given.

PROCEDURE

ICG parathyroid angiography

Injection of 3,5 mL of indocyanine green intravenously and perform angiography of parathyroid glands after thyroid removal.

DRUG

Parathyroid supplementation

Supplementration with Calcimagon D3 Forte (1gr Calcium and 800 IU of 25-OH-vitamin D) from surgery day to up to 10 days afeter surgery.

Sponsors & Collaborators

• Geneva University, School of medicine

  collaborator UNKNOWN

• University Hospital, Geneva

  lead OTHER

Principal Investigators

• Frédéric Triponez, Professor · University Hospital, Geneva

• Wolfram Karenovics, SPR · University Hospital, Geneva

• Frédéric Ris, Consultant · University Hospital, Geneva

• Valentina Belfontali, Resident · University Hospital, Geneva

• Jordi Vidal Fortuny, SPR · University Hospital, Geneva

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

80 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2014-09-30

Primary Completion

2016-02-29

Completion

2016-02-29

Countries

• Switzerland

Study Locations