Prevalence of DIAbetic RETinopathy and Impact of Genetic Factors in the Development of Diabetic Retinopathy of Patients With Type 1 and 2 Diabetes Mellitus in SlovaKia

Summary

The aim of the study is to find out prevalence and individual stages of Diabetic Retinopathy in patients with type 1 and type 2 DM verified based on complex ophthalmologic measurements in Slovak Republic. The outcome of the project will be epidemiology survey, prevalence of diabetic retinopathy (DR) and diabetic macular edema (DME) in relation to type and duration of diabetes mellitus and risk factors. Project will also identify genetic factors linked with the diseases.

Conditions

• Diabetic Retinopathy
• Diabetic Macular Edema
• Diabetes Mellitus

Interventions

GENETIC

Studied cohort

For the purpose of DNA isolation prior to genetic analysis of patients two samples of peripheral blood will be taken; first in the volume of 3.5 ml and second in the volume of 9 ml from each patient included into the study.

Sponsors & Collaborators

• Medirex Group Academy

  collaborator UNKNOWN

• Slovak Technical University

  collaborator UNKNOWN

• Comenius University

  collaborator OTHER

• Novartis Slovakia, s.r.o.

  lead INDUSTRY

Principal Investigators

• Dagmar Buckova, M.D. · Novartis Slovakia

• Peter Carnogursky, MSc. · Novartis Slovakia, s.r.o.

• Svetlana Sefcikova, MD · Novartis Slovakia, s.r.o.

• Pavol Tison, MD · Novartis Slovakia, s.r.o.

• Iveta Tvrda, MD · Novartis Slovakia, s.r.o.

• Daniela Gasperikova, MSc., PhD. · Novartis Slovakia, s.r.o.

• Ivana Hojsikova, RNDr. · Medirex Group Academy

• Ludevit Kadasi, RNDr., DrSc. · Comenius University

• Iwar Klimes, Prof., MD, DrSc. · Novartis Slovakia, s.r.o.

• Peter Jackuliak, MD · University Hospital Bratislava

• Vladimir Krasnik, MD PhD. · University Hospital Bratislava

• Emil Martinka, MD, PhD. · National Institute for Endocrinology and Diabetology

• Marian Mokan, Prof. MD DrSc. · Jesenius University Martin

• Zuzana Nemethyova, MD · Diabetology Dispensary Bratislava

• Marta Ondrejkova, MD PhD. · F.D. Roosevelt Hospital Banska Bystrica

• Jana Stefanickova, MD · University Hospital Bratislava

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2015-02-28

Primary Completion

2015-11-30

Completion

2015-11-30