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Ketamine and Glutamate After Brain Injury : a Microdialysis Study

NCT02232347 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2014-09-05

No results posted yet for this study

Summary

The objective of the study is to compare the effects of 48 hours ketamine infusion versus sufentanil infusion on brain glutamate concentrations measured with microdialysis after traumatic brain injury.

We hypothesize that ketamine infusion will decrease high glutamate values faster than sufentanil.

Conditions

  • Head Trauma

Interventions

DRUG

Ketamine

DRUG

Sufentanil

Sponsors & Collaborators

  • Pierre-Julien CUNGI

    lead OTHER

Principal Investigators

  • Ambroise MONTCRIOL, MD · Direction Centrale du Service de Santé des Armées

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-10-31
Primary Completion
2016-10-31
Completion
2017-05-31

Countries

  • France

Study Locations

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Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02232347 on ClinicalTrials.gov