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The Potential of a Low Glutamate Diet as a Treatment for Pediatric Epilepsy

NCT04545346 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 45

Last updated 2022-07-20

No results posted yet for this study

Summary

The study is investigating if following the low glutamate diet for 1 month, as compared to care as usual, can improve seizure frequency, severity, and duration; cognitive functioning; and/or quality of life in children with epilepsy.

Conditions

  • Epilepsy in Children
  • Epilepsy in Youth
  • Randomized Controlled Trial
  • Refractory Epilepsy
  • Diet Intervention

Interventions

OTHER

Low Glutamate diet

Participants will be given extensive online dietary training and assigned to follow the low glutamate diet for one month. The low glutamate diet reduces the consumption of free glutamate, while optimizing dietary micronutrient and antioxidant intake.

Sponsors & Collaborators

  • Children's National Research Institute

    collaborator OTHER

  • American University

    lead OTHER

Principal Investigators

  • Kathleen Holton, MPH, PhD · American University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
2 Years
Max Age
21 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-10-15
Primary Completion
2022-06-15
Completion
2022-06-15

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04545346 on ClinicalTrials.gov