Ketogenic Diet for Refractory Status Epilepticus

Summary

This research is being done to observe the safety, tolerability, side effects, and effectiveness of the ketogenic diet in people with continuous seizures (status epilepticus) being treated in a neurointensive care unit.

Conditions

• Status Epilepticus
• Seizure
• Epilepsy
• Refractory Status Epilepticus
• Medically Resistant Status Epilepticus

Interventions

DIETARY_SUPPLEMENT

Ketogenic diet

4:1 ratio fat: carbohydrates and protein ketogenic liquid via enteral feed

Sponsors & Collaborators

• Mayo Clinic

  collaborator OTHER

• Queen's Medical Center

  collaborator OTHER

• Rush University Medical Center

  collaborator OTHER

• Oregon Health and Science University

  collaborator OTHER

• Thomas Jefferson University

  collaborator OTHER

• Intermountain Medical Center

  collaborator OTHER

• NYU Langone Health

  collaborator OTHER

• University of Rochester

  collaborator OTHER

• Johns Hopkins University

  lead OTHER

Principal Investigators

• Mackenzie C. Cervenka, MD · Johns Hopkins University

Study Design

Allocation

NA

Purpose

TREATMENT

Masking

NONE

Model

SINGLE_GROUP

Eligibility

Min Age

18 Years

Max Age

80 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2012-11-30

Primary Completion

2017-03-31

Completion

2017-03-31

Countries

• United States

Study Locations