Cardiac Output and Duplex Sonography in Carotid Endarterectomy

Summary

The aim of this study is to investigate the differences between the cardiac output and the cerebral blood-flow between a regional anesthesia (RA) and a general anesthesia (GA) in a randomized, controlled, single center study at the Medical University Innsbruck, Department of Anesthesia and Intensive Care Medicine.

Conditions

• Carotid Stenosis

Interventions

PROCEDURE

Regional anesthesia

Regional anesthesia

PROCEDURE

General anesthesia

General anesthesia

DEVICE

Transcranial Doppler ultrasonography

6x for 4 hours

PROCEDURE

blood gas analysis

6 x 3 ml blood withdrawal (18 ml) within 4 hours

PROCEDURE

invasive arterial blood pressure measurement

before operation, 8 hours, as done in clinical routine

PROCEDURE

arterial blood gas measurement

perioperative, 4-6 times within 8 hours, as done in clinical routine

BEHAVIORAL

Neurological Control

perioperative, 2-3 days, as done in clinical routine

BEHAVIORAL

NIRS monitoring

perioperative, for 5 hours, as done in clinical routine

DEVICE

oxygen supply (not invasive 'Vigileo')

perioperative for 5 hours, as done in clinical routine

Sponsors & Collaborators

• Medical University Innsbruck

  lead OTHER

Principal Investigators

• Corinna Velik-Salchner, PrivDoz.Dr. · Medical University Innsbruck

Study Design

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2014-07-31

Primary Completion

2017-07-31

Completion

2017-07-31

Countries

• Austria

Study Locations