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Microparticles in Severe Aortic Stenosis

NCT02193035 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 15

Last updated 2016-04-13

No results posted yet for this study

Summary

Microparticles are small cell fragments that can induce fat plaques, calcification and formation of thrombus. They can be released through multiple stimulations, but also the high flow of blood through partially obstructed aortic valves.

In patients with severely obstructed aortic valves the investigators hypothesize that microparticles levels will be elevated and that they will go down after percutaneous treatment of the valves.

Conditions

  • Aortic Valve Stenosis

Interventions

OTHER

Microparticle levels

Microparticle levels will be evaluated with flow cytometry and nanoparticle tracking analysis

Sponsors & Collaborators

  • InCor Heart Institute

    lead OTHER

Principal Investigators

  • Pedro Lemos, MD PhD · Heart Institute - InCor. University of Sao Paulo Medical School

  • Julio F Marchini, MD PhD · Heart Institute - InCor. University of Sao Paulo Medical School

Study Design

Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-06-30
Primary Completion
2015-06-30
Completion
2015-06-30

Countries

  • Brazil

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02193035 on ClinicalTrials.gov