Validation of the Wisconsin Stone-QOL

Summary

The overall purpose of this study is to evaluate criterion-related validity of a newly-developed disease-specific instrument to assess the health-related quality of life (HRQOL) of patients who have had kidney stones. Specific aims of this study are:

1. Aim 1. Evaluate the population/external validity (generalizability) of the Wisconsin Stone-QOL by answering the question, "Is the Wisconsin Stone-QOL useful for assessing the HRQOL of patients who form kidney stones from a broad region of North America?"
2. Aim 2. Assess the ability of the Wisconsin Stone-QOL to detect changes within patients related to stone interventions and other disease-specific outcomes by answering the question, "Is the Wisconsin Stone-QOL sensitive to changes in stone-related outcomes within individuals?"

Conditions

• Urolithiasis
• Nephrolithiasis
• Kidney Stones

Interventions

OTHER

Wisconsin Stone-QOL survey

Patients will complete a health-related quality of life survey at multiple time points at enrollment and at multiple time points thereafter.

Sponsors & Collaborators

• University of Florida

  collaborator OTHER

• University of California, San Diego

  collaborator OTHER

• University of North Carolina

  collaborator OTHER

• Dartmouth College

  collaborator OTHER

• The Cleveland Clinic

  collaborator OTHER

• University of British Columbia

  collaborator OTHER

• University of Texas

  collaborator OTHER

• University of California, Davis

  collaborator OTHER

• University of California, Irvine

  collaborator OTHER

• University of California, San Francisco

  collaborator OTHER

• University of Washington

  collaborator OTHER

• Penn State University

  collaborator OTHER

• McGill University

  collaborator OTHER

• University of Pittsburgh

  collaborator OTHER

• Université de Montréal

  collaborator OTHER

• University of Wisconsin, Madison

  lead OTHER

Principal Investigators

• Kristina L Penniston, PhD · University of Wisconsin Department of Urology, School of Medicine & Public Health

• Stephen Y Nakada, MD · University of Wisconsin Department of Urology, School of Medicine & Public Health

Study Design

Allocation

NA

Purpose

OTHER

Masking

NONE

Model

SINGLE_GROUP

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2014-07-31

Primary Completion

2022-05-31

Completion

2023-06-30

Countries

• United States

Study Locations