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CONTRAST (Can cONTrast Injection Better Approximate FFR compAred to Pure reSTing Physiology?)

NCT02184117 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 763

Last updated 2016-05-16

No results posted yet for this study

Summary

The purpose of this study is to determine the diagnostic performances of iodine contrast medium and resting conditions to predict fractional flow reserve (FFR). Reference FFR will be measured using standard adenosine. We hypothesize that contrast FFR will offer superior diagnostic agreement compared to resting conditions.

Conditions

Interventions

DRUG

Adenosine

Intracoronary or intravenous adenosine to induce hyperemia for reference FFR

DRUG

Contrast Media

Intracoronary injection of contrast medium to induce hyperemia for "contrast FFR"

DRUG

Resting conditions

Baseline measurement of aortic and coronary pressures

Sponsors & Collaborators

  • Abbott Medical Devices

    collaborator INDUSTRY

  • The University of Texas Health Science Center, Houston

    lead OTHER

Principal Investigators

  • Nils P Johnson, MD, MS · University of Texas Medical School at Houston

  • William F Fearon, MD · Stanford University

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-07-31
Primary Completion
2015-05-31
Completion
2015-05-31

Countries

  • United States
  • Belgium
  • France
  • Italy
  • Netherlands
  • Portugal
  • South Korea
  • Sweden
  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02184117 on ClinicalTrials.gov