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Multivariable Assessment of Coronary Artery Disease Using Cardiac CT Imaging

NCT00857792 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 120

Last updated 2016-05-11

Study results available
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Summary

The investigators goals are:

1. to develop software for quantitative volumetric analysis of myocardial perfusion from MDCT images
2. to test its ability to accurately determine the presence, location, extend and severity of perfusion abnormalities in agreement with conventional diagnostic techniques (ICA and MPI) in patients with normal and abnormal coronary arteries and/or perfusion patterns
3. to test this approach in patients undergoing vasodilator stress tests with MDCT imaging in combination with the new vasodilator stress agent Regadenoson.

Conditions

  • Coronary Disease

Interventions

DRUG

regadenoson

Subjects will be given a single dose of regadenoson (0.4 mg, i.e. 5 ml i.v. bolus).

Sponsors & Collaborators

  • Astellas Pharma Inc

    collaborator INDUSTRY

  • University of Chicago

    lead OTHER

Principal Investigators

  • Victor Mor-Avi, PhD · University of Chicago

Study Design

Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-03-31
Primary Completion
2013-01-31
Completion
2013-01-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00857792 on ClinicalTrials.gov