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The Lipid Profile of the Skin Surface in Acne

NCT02180425 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2017-05-30

No results posted yet for this study

Summary

The purpose of this study is to evaluate the differences in the skin lipid profile of patients with and without acne. Secondly, the goal is to learn more about what the effects of retinoinds (topical and systemic) are on the the skin lipid profile. We hypothesize that the skin lipid profile of subjects with acne will be lower in inflammatory lipids in comparison to subjects without acne.

Conditions

Interventions

DRUG

Tretinoin or Adapalene

Subjects will apply a pea sized amount of topical retinoid cream once daily at night for 30 days. Subjects will return for a follow-up visit.

DRUG

Isotretinoin

Subjects will take one pill once daily for 5 months. Subjects will return after 1 month and after 4-5 months of treatment for skin lipid profiling.

Sponsors & Collaborators

  • University of California, Davis

    lead OTHER

Principal Investigators

  • Raja K Sivamani, MD · UC Davis

Eligibility

Min Age
12 Years
Max Age
30 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2013-11-30
Primary Completion
2015-05-31
Completion
2015-07-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02180425 on ClinicalTrials.gov