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De Novo Lipogenesis of Sebaceous Glands in Acne

NCT02620813 · Status: COMPLETED · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 32

Last updated 2021-08-05

No results posted yet for this study

Summary

There are two purposes of this study:

1. First, the investigators want to see what the differences are in de novo sebaceous lipid production of people with and without acne.
2. Secondly, the investigators want to know what happens to sebaceous gland de novo lipid production before and after treatment with topical tretinoin and oral isotretinoin.

Conditions

  • Acne Vulgaris

Interventions

DRUG

Tretinoin

Subjects will apply 0.5% tretinoin cream nightly to their face for a total of 12 weeks.

DRUG

Isotretinoin

Subjects will take isotretinoin as prescribed by their dermatologist.

Sponsors & Collaborators

  • University of California, Davis

    lead OTHER

Study Design

Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
15 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-10-31
Primary Completion
2017-10-12
Completion
2017-10-12

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02620813 on ClinicalTrials.gov