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18F-DOPA-PET in Planning Surgery in Patients With Gliomas

NCT02020720 · Status: COMPLETED · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 72

Last updated 2025-01-23

No results posted yet for this study

Summary

This pilot clinical trial studies fluorine F 18 fluorodopa (18F-DOPA)-positron emission tomography (PET) in planning surgery in patients with gliomas. New imaging procedures, such as 18F-DOPA-PET scan, may help find gliomas and may help in planning surgery.

Conditions

  • Malignant Glioma
  • Recurrent Brain Neoplasm

Interventions

PROCEDURE

Biopsy

Undergo image-guided biopsy

PROCEDURE

Computed Tomography

Undergo 18F-DOPA-PET/CT

PROCEDURE

Diffusion Weighted Imaging

Undergo DTI

DRUG

Fluorine F 18 Fluorodopa

Undergo 18F-DOPA-PET/CT

OTHER

Laboratory Biomarker Analysis

Correlative studies

PROCEDURE

Perfusion Magnetic Resonance Imaging

Undergo pMRI

PROCEDURE

Positron Emission Tomography

Undergo 18F-DOPA-PET/CT

PROCEDURE

Therapeutic Conventional Surgery

Undergo stereotactic craniotomy

Sponsors & Collaborators

  • National Cancer Institute (NCI)

    collaborator NIH

  • Mayo Clinic

    lead OTHER

Principal Investigators

  • Nadia N. Laack, M.D. · Mayo Clinic in Rochester

  • Debra H. Brinkmann, Ph.D. · Mayo Clinic in Rochester

Study Design

Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
7 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-01-22
Primary Completion
2019-10-25
Completion
2024-01-10

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02020720 on ClinicalTrials.gov