A Study In Healthy Elderly People To Evaluate Safety, Toleration, Pharmacokinetics and Pharmacodynamics of Multiple Oral Doses Of PF-06743649
NCT02170012 · Status: TERMINATED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 24
Last updated 2015-03-17
Summary
The purpose of this study in healthy elderly people is to evaluate safety, toleration and time course of plasma concentration of multiple oral doses of PF-06743649- The pharmacodynamic activity of PF-06743649 will also be assessed.
Conditions
- Healthy Elderly
Interventions
- DRUG
-
PF-06743649
20 mg tablet once daily dosing for 14 days
- DRUG
-
Placebo tablet once daily dosing for 14 days
- DRUG
-
PF-06743649
To be decided dose, tablet once daily dosing for 14 days
- DRUG
-
Placebo tablet once daily dosing for 14 days
- DRUG
-
PF-06743649
To be decided dose, tablet once daily dosing for 14 days
- DRUG
-
Placebo tablet once daily dosing for 14 days
- DRUG
-
PF-06743649
To be decided dose, tablet once daily dosing for 14 days
- DRUG
-
Placebo tablet once daily dosing for 14 days
- DRUG
-
PF-06743649
To be decided dose, tablet once daily dosing for 14 days
- DRUG
-
Placebo tablet once daily dosing for 14 days
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Pfizer CT.gov Call Center · Pfizer
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 65 Years
- Max Age
- 85 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2014-07-31
- Primary Completion
- 2014-09-30
- Completion
- 2014-09-30
Countries
- United States
Study Locations
More Related Trials
-
A Study To Evaluate The Safety And Tolerability Of Different Doses Of PF-03049423 In Healthy Adult Volunteers And Healthy Older Volunteers
NCT01161069 ·Status: COMPLETED ·Phase: PHASE1
-
Evaluation Of Safety, Tolerability And Pharmacokinetics Of Single And Multiple Doses Of PF-06730512
NCT03146065 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Evaluate Safety, Toleration and Time Course of Plasma Concentration of Multiple Oral Doses of PF-06273340 in Healthy Subjects of Two AgeGroups, Aged 18-55 Years (Group 1) and Aged 56-75 Years (Group 2)
NCT01934738 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Evaluate the Safety, Tolerability and Pharmacokinetics of PF-04958242 in Healthy Adult Volunteers
NCT01238679 ·Status: TERMINATED ·Phase: PHASE1
-
Single Dose Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Study Of PF-06291874 In Healthy Adult Subjects
NCT01794364 ·Status: COMPLETED ·Phase: PHASE1
-
Evaluation Of Safety, Tolerability And Pharmacokinetics Of Single And Multiple Doses Of Compound PF-06823859
NCT02766621 ·Status: COMPLETED ·Phase: PHASE1
-
Safety and Tolerability Study of Multiple Doses of PF-06305591
NCT01776619 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Learn How the Study Medicine PF-07899895 Are Tolerated and Act in the Body of Healthy Adults
NCT06137729 ·Status: TERMINATED ·Phase: PHASE1
-
Study Of Single And Multiple Ascending Doses Of PF-07054894 In Healthy Adult Participants
NCT04388878 ·Status: COMPLETED ·Phase: PHASE1
-
A First-In-Human Study of the Study Medicine, Called PF-07291177, in Healthy Adult Participants
NCT05434091 ·Status: WITHDRAWN ·Phase: PHASE1
-
A Study To Evaluate The Safety, Tolerability, Pharmacokinetics, And Pharmacodynamics Of PF-03882845 In Healthy Volunteers
NCT00971802 ·Status: COMPLETED ·Phase: PHASE1
-
A Multiple Dose Study To Determine Safety, Tolerability, and Pharmacokinetics Of PF-04634817 In Healthy Adult Subjects
NCT01140672 ·Status: COMPLETED ·Phase: PHASE1
-
Study To Evaluate Safety, Tolerability, And Pharmacokinetics Of PF-06473871 In Normal Healthy Adults
NCT01753791 ·Status: COMPLETED ·Phase: PHASE1
-
Group Study To Investigate The Safety, Toleration And Pharmacokinetics Of Multiple Oral Doses Of PF-04531083 In Healthy Subjects
NCT01012310 ·Status: COMPLETED ·Phase: PHASE1
-
Single Dose Study of PF-06815345 in Healthy Subjects
NCT02654899 ·Status: TERMINATED ·Phase: PHASE1
-
A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of PF-06842874 in Healthy Participants
NCT04124653 ·Status: COMPLETED ·Phase: PHASE1
-
A Study In Healthy People To Evaluate Safety, Toleration And Time Course Of Plasma Concentration Of Multiple Oral Doses Of PF-04895162
NCT01691274 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Learn How Different Amounts of the Study Medicine Called PF-07314470 Are Tolerated and Act in the Body in Healthy Adults
NCT06821750 ·Status: TERMINATED ·Phase: PHASE1
-
First-In-Human Study Of Single And Multiple Ascending Doses Of PF-06751979
NCT02509117 ·Status: COMPLETED ·Phase: PHASE1
-
A Study To Look At Safety And Blood Concentrations After Multiple Doses Of PF-03382792 In Healthy Elderly Individuals
NCT01089738 ·Status: WITHDRAWN ·Phase: PHASE1
-
Safety and Tolerability of PF-06818883 in Healthy Subjects
NCT03020784 ·Status: TERMINATED ·Phase: PHASE1
-
A Single Dose Study Of PF-06291874 In Healthy Adult Subjects
NCT01499017 ·Status: TERMINATED ·Phase: PHASE1
-
A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Repeat Doses of PF-06372865 in Healthy Subjects
NCT03351751 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Learn How Different Amounts of the Study Medicine Called PF-07940369 Are Tolerated and Act in the Body in Healthy Adults.
NCT06532383 ·Status: COMPLETED ·Phase: PHASE1
-
Evaluation of Safety, Tolerability and Pharmacokinetics of Single Dose of PF-06480605 in Japanese Healthy Participants
NCT04269538 ·Status: COMPLETED ·Phase: PHASE1