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Esophageal Bolus Transit in Newborns With Gastroesophageal Reflux Disease

NCT02167984 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 61

Last updated 2018-05-15

No results posted yet for this study

Summary

Esophageal dysmotility due to immaturity could promote impaired bolus transit during esophageal swallow events,thus influencing gastroesophageal reflux (GER) clearance.

Aim of this study was to describe esophageal bolus transit characteristics during swallow and to evaluate the relationship between esophageal swallow (ES) and GER in newborns with gastroesophageal reflux disease symptoms using multichannel intraluminal impedance.

The simultaneous analysis of swallow and GER events in newborns undergone MII/pH monitoring could provide useful information to better understand the physiopathology of gastroesophageal reflux disease (GERD) and could help clinicians to identify newborns with prolonged esophageal clearance time, making the recommendations for further tests and the therapeutic approach more accurate

Conditions

  • Gastroesophageal Reflux

Sponsors & Collaborators

  • University of Turin, Italy

    lead OTHER

Principal Investigators

  • Francesco Cresi, MD · University of Turin, Italy

Eligibility

Min Age
1 Day
Max Age
90 Days
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-01-31
Primary Completion
2013-03-31
Completion
2013-03-31

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02167984 on ClinicalTrials.gov