Gastric Accommodation and Gastroesophageal Reflux
NCT01078064 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 10
Last updated 2019-03-21
Summary
Gastroesophageal reflux events generally happen during relaxation of lower esophageal sphincter. This relaxation is a reflex that is triggered by gastric stimuli. The investigators hypothesize that abnormal relaxation of the gastric wall after a meal may lead to reflux events. To test this hypothesis, a study was designed to measure the gastric accommodation in patients undergoing esophageal impedance monitoring.
Conditions
- Gastroesophageal Reflux Disease
Sponsors & Collaborators
-
Nationwide Children's Hospital
lead OTHER
Principal Investigators
-
Rodrigo S Machado, MD, PhD · Nationwide Children's Hospital
-
Beth Skaggs, CCRC · Nationwide Children's Hospital
Eligibility
- Min Age
- 1 Year
- Max Age
- 30 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2010-03-31
- Primary Completion
- 2010-11-30
- Completion
- 2010-11-30
Countries
- United States
Study Locations
More Related Trials
-
Esophageal Bolus Transit in Newborns With Gastroesophageal Reflux Disease
NCT02167984 ·Status: COMPLETED
-
High Dosage Esomeprazole and Baclofen for Therapy of Gastroesophageal Reflux Disease
NCT00461604 ·Status: COMPLETED
-
Efficacy and Safety of Esomeprazole Once Daily for the Treatment of GERD in Neonatal Patients
NCT00427635 ·Status: COMPLETED ·Phase: PHASE3
-
Pharmacogenetic Testing in Children With Persistent Gastroesophageal Reflux Disease
NCT03005080 ·Status: COMPLETED
-
Structure and Function of the Gastro-esophageal Junction
NCT01053585 ·Status: COMPLETED ·Phase: NA
-
Esomeprazole for Treatment of GERD in Pediatric Patients
NCT00228527 ·Status: COMPLETED ·Phase: PHASE4
-
The Gastrointestinal Microbiome of Infants With GERD and PPI Therapy: a Pilot Study
NCT02359604 ·Status: COMPLETED ·Phase: NA
-
Treatment Of Gastroesophageal Reflux Disease By Endoscopic Fundoplication, A Placebo-Controlled Study
NCT00235677 ·Status: COMPLETED ·Phase: PHASE3
-
Management of Esophagitis Following Repair of Esophageal Atresia
NCT03619408 ·Status: UNKNOWN
-
Important Correlation Between Anxiety and Reflux Symptoms in Patients With Gastroesophageal Reflux Disease
NCT06151067 ·Status: COMPLETED
-
A Study to Evaluate the Pharmacokinetics, Pharmacodynamics and Safety of Vonoprazan in Adolescents With Symptomatic Gastroesophageal Reflux Disease
NCT05343364 ·Status: COMPLETED ·Phase: PHASE1
-
An Investigation of the EndoStim® Lower Esophageal Sphincter (LES) Stimulation System for the Treatment of Reflux
NCT02749071 ·Status: TERMINATED ·Phase: NA
-
Mucosal Impedance in Pediatric Population
NCT02320981 ·Status: COMPLETED
-
Study Evaluating Pantoprazole in Children With Gastroesophageal Reflux Disease (GERD)
NCT00300755 ·Status: COMPLETED ·Phase: PHASE3
-
A Placebo Controlled Trial With Baclofen for the Treatment of GERD Patients With Incomplete PPI Response
NCT03835442 ·Status: COMPLETED ·Phase: NA
-
Study to Evaluate the Pharmacokinetics and Safety of Dexlansoprazole in Pediatric Subjects With Symptomatic Gastroesophageal Reflux Disease
NCT01045096 ·Status: COMPLETED ·Phase: PHASE1
-
Phase 3/Safety & Efficacy of Esomeprazole in Infants
NCT00468559 ·Status: COMPLETED ·Phase: PHASE3
-
Reletex for Nausea in GERD Patients
NCT01582100 ·Status: TERMINATED ·Phase: NA
-
A Study to Evaluate the Effect of Lansoprazole on Infants With Gastroesophageal Reflux Disease.
NCT00220818 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Check the Safety of Dexlansoprazole and Learn if it Can Treat Symptomatic Nonerosive Gastroesophageal Reflux Disease in Children 2 to 11 Years Old
NCT02616302 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Longitudinal Study of Children With a Chronic Cough and the Impact of Gastroesophageal Reflux
NCT00771706 ·Status: WITHDRAWN ·Phase: PHASE3
-
Study Evaluating the Efficacy and Safety of Pantoprazole in Infants With Symptomatic Gastroesophageal Reflux Disease (GERD)
NCT00365300 ·Status: COMPLETED ·Phase: PHASE3
-
The Effect of Corticotrophin-releasing Hormone (CRH) on Esophageal Motility in Healthy Volunteers
NCT02736734 ·Status: COMPLETED ·Phase: PHASE4
-
Sleep Position May Reduce Acid Reflux Symptoms at Night
NCT02320968 ·Status: TERMINATED ·Phase: NA
-
A Study to Evaluate Vonoprazan in Children Who Have Symptomatic Gastroesophageal Reflux Disease
NCT06106022 ·Status: COMPLETED ·Phase: PHASE1