Incubator Weaning of Moderately Preterm Infants

Summary

The objective of this proposal is to evaluate whether weaning from an incubator to a crib at lower versus higher weight, 1600g or 1800g will result in shorter length of hospital stay among moderately preterm infants.

The hypothesis of this study is that length of hospital stay (from birth to discharge) will be decreased among moderate preterm infants weaned from an incubator to an open crib at a lower versus higher weight, 1600g vs. 1800g.

Conditions

• Infant, Newborn
• Infant, Moderate Preterm

Interventions

PROCEDURE

Weaning from an incubator at a lower weight (1600 grams)

Infants will be weaned from an incubator at a lower weight (1600 grams)

PROCEDURE

Weaning from an incubator at a higher weight (1800 grams)

Infants will be weaned from an incubator at a higher weight (1800 grams)

Sponsors & Collaborators

• Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

  collaborator NIH

• NICHD Neonatal Research Network

  lead NETWORK

Principal Investigators

• Michele C Walsh, MD · Case Western Reserve University, Rainbow Babies and Children's Hospital

• Myra Wyckoff, MD · University of Texas, Southwestern Medical Center at Dallas

• Seetha Shankaran, MD · Wayne State University

• David Carlton, MD · Emory University

• Kurt Schibler, MD · Children's Hospital Medical Center, Cincinnati

• Brenda B Poindexter, MD · Indiana University

• Abbot Laptook, MD · Brown University, Women & Infants Hosptial of Rhode Island

• Krisa P Van Meurs, MD · Stanford University

• Waldemar Carlo, MD · University of Alabama at Birmingham

• Kathleen A Kennedy, MD · The University of Texas Health Science Center, Houston

• Mike Cotten, MD · Duke University

• Edward F Bell, MD · University of Iowa

• Kristi Watterberg, MD · University of New Mexico

• Barbara Schmidt, MD · University of Pennsylvania

• Carl T D'Angio, MD · University of Rochester

• Uday Devaskar, MD · University of California, Los Angeles

• Pablo Sanchez, MD · Research Institute at Nationwide Children's Hospital

• William Truog, MD · Children's Mercy Hospital Kansas City

• Abhik Das, PhD · RTI International

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

29 Weeks

Max Age

34 Weeks

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2015-02-28

Primary Completion

2016-07-31

Completion

2017-06-30

Countries

• United States

Study Locations