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Effect of Working Memory Training on ADHD Brain Function

NCT02151396 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 37

Last updated 2014-05-30

No results posted yet for this study

Summary

There is evidence both that computer-administered cognitive training can improve ADHD working memory deficits and that this type of training in non-ADHD enhances normal working memory ability by altering brain activity in prefrontal cortex and the parietal lobe. However, no study has characterized brain activity changes following working memory training in ADHD to understand what neural changes occur when cognitive deficits are remedied. This R21 exploratory study will examine the neural basis of cognitive training treatment gains in working memory, ADHD symptoms, and various other executive abilities. We will test the hypothesis that working memory training increases frontoparietal brain activation and examine other regions to see if there is any evidence for "neural compensation" (i.e., engagement of brain regions after training that are not normally recruited for task performance).

Conditions

  • Attention-Deficit/Hyperactivity Disorder (Combined-subtype)

Interventions

BEHAVIORAL

Working memory training

DEVICE

Functional magnetic resonance imaging (fMRI)

Sponsors & Collaborators

  • National Institutes of Health (NIH)

    collaborator NIH

  • Hartford Hospital

    lead OTHER

Principal Investigators

  • Michael C. Stevens, Ph.D. · Hartford Hospital

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
13 Years
Max Age
17 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-07-31
Primary Completion
2013-02-28
Completion
2013-02-28

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02151396 on ClinicalTrials.gov