MedTrace Logo

Comorbidities and Virologic Outcome Among Patients on Anti-retroviral Therapy in Rural Lesotho

NCT02126696 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 1754

Last updated 2016-04-21

No results posted yet for this study

Summary

This study is conducted in a cohort of HIV-positive patients on first-line anti-retroviral therapy (ART) in rural health facilities in Lesotho, Southern Africa. It examines virologic treatment failure as well as chronic communicable and non-communicable comorbidities among patients on ART. The study has two phases. Phase 1 consists of a cross-sectional survey to determine prevalence of treatment failure as well as the prevalence of the following comorbidities: diabetes mellitus, arterial hypertension, dyslipidemia, depression, alcohol use disorder, hepatitis B and hepatitis C. Phase 2 is a cohort study, where patients with treatment failure or a comorbidity or both are followed-up for 12 months.

Conditions

Sponsors & Collaborators

  • Swiss Foundation for Excellence and Talent in Biomedical Research

    collaborator UNKNOWN

  • SolidarMed - Swiss Organization for Health in Africa

    collaborator UNKNOWN

  • University of Basel

    collaborator OTHER

  • Central Laboratories, University Hospitals Basel-Land (Liestal)

    collaborator UNKNOWN

  • Swiss Tropical & Public Health Institute

    lead OTHER

Principal Investigators

  • Niklaus D Labhardt, MD, MIH · Swiss Tropical & Public Health Institute

  • Christoph Hatz, Prof · Swiss Tropical & Public Health Institute

  • Thomas Klimkait, Prof · Department of Biomedicine, University of Basel

Eligibility

Min Age
6 Months
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-05-31
Primary Completion
2014-11-30
Completion
2015-12-31

Countries

  • Lesotho

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02126696 on ClinicalTrials.gov