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Association Between Fluid Administration, Oxytocin Administration, and Fetal Heart Rate Changes

NCT02121184 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 172

Last updated 2024-05-29

Study results available
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Summary

Fetal heart rate patterns are an important parameter in the diagnosis of non-reassuring fetal status. Combined-spinal epidural analgesia is a method of initiating labor analgesia used by approximately 90% of the parturients at Prentice Women's Hospital. Optimizing the variables which could affect fetal heart rate patterns at the time of initiation of analgesia, such as fluid administration and oxytocin management, could help us provide better care for our patients and their fetuses.

Hypotheses: Patients who receive a 1000 mL fluid bolus and lower rates of oxytocin administration will have fewer non-reassuring fetal heart rate (FHR) changes.

Conditions

  • Pregnancy
  • Labor Pain

Interventions

DRUG

Routine oxytocin

per regular oxytocin protocols

DRUG

Half-dose oxytocin

The dose of oxytocin currently being administered will be halved and not increased until after 60 minutes initiation of labor analgesia

Sponsors & Collaborators

Principal Investigators

  • Charles Hogue, M.D. · Northwestern University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-04-30
Primary Completion
2021-09-21
Completion
2021-09-21

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02121184 on ClinicalTrials.gov