Blood Products in Cardiac Surgery

Summary

Blood transfusion is a common procedure essential for the treatment of patients undergoing cardiac surgery. Inappropriate transfusions, however, not only incur needless healthcare costs, but increase unnecessary risks due to transfusion reactions and infectious and immunomodulative causes. Safe and appropriate patient care requires evaluated blood component prescription practices.

Practically all patients undergoing cardiac surgery in Finland have a blood product booking from the Finnish Red Cross Blood Service. This registry contains large volumes of transfusion-related information on all Finnish patients undergoing cardiac surgery in Finnish centers. Participating hospitals were scattered to all geographical areas in Finland and concentrated to the most populated regions.

Data on the blood product use, laboratory findings one month pre-operatively and 12 months post-operatively were available.

Finnish hospitals have been required to provide information on hospital visits for the Finnish National Research and Development Centre for Welfare and Health for healthcare planning purposes. We used in part the original data sent by hospitals to the Finnish Hospital Discharge Register (FHDR).

Conditions

• Anemia
• Renal Impairment
• Thrombocytopenia

Sponsors & Collaborators

• Finnish Red Cross Blood Service

  collaborator OTHER

• Central Finland Hospital District

  collaborator OTHER

• Turku University Hospital

  collaborator OTHER_GOV

• Oulu University Hospital

  collaborator OTHER

• Tampere University Hospital

  collaborator OTHER

• Kuopio University Hospital

  collaborator OTHER

• Helsinki University Central Hospital

  collaborator OTHER

• Satakunta Central Hospital

  collaborator OTHER

• University of Turku

  lead OTHER

Principal Investigators

• Pirjo Mustonen, MD, PhD · Central Finland Central Hospital

• Juhani Airaksinen, Prof · Turku University Hospital and University of Turku

• Fausto Biancari, MD, PhD · Oulu University Hospital

• Tuomas O Kiviniemi, Md, PhD · Turku University Hospital and University of Turku

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2002-01-31

Primary Completion

2012-12-31

Completion

2012-12-31