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Vaginal Administration of Metformin in PCOS Patients.

NCT02026869 · Status: UNKNOWN · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 200

Last updated 2014-01-03

No results posted yet for this study

Summary

Polycystic ovary syndrome is a common cause of irregular periods, poor ovulation and delay in achieving pregnancy. Certain drugs may help improve ovarian activity in such women as metformin. Oral administration of metformin is accompanied by undesirable side effects. The vagina proved to be a good alternative to the oral route for other drugs. Using metformin through the vagina and avoidance of such side effects, while maintaining its effectiveness, would help women to better tolerate this drug.

Conditions

  • PCOS

Interventions

DRUG

Metformin

Metformin is taken either orally or vaginally every 12 hours

Sponsors & Collaborators

  • Assiut University

    lead OTHER

Principal Investigators

  • AHMED NASR, MD · Professor, Women's Health Hospital, Assiut University, Egypt.

  • MAGDY AMIN, MD · Associate professor, dept. of Obstetrics & gynecology, Sohag University, Egypt

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
FACTORIAL

Eligibility

Min Age
20 Years
Max Age
35 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-01-31
Primary Completion
2013-06-30
Completion
2014-02-28

Countries

  • Egypt

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02026869 on ClinicalTrials.gov