Effects of Metformin on Metabolic and Reproductive Outcomes in Chinese PCOS Patients
NCT05463627 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 1440
Last updated 2022-07-19
Summary
Polycystic ovary syndrome (PCOS) is a reproductive endocrine disease characterized by reproductive and metabolic abnormalities, which is a crucial cause of female infertility and an essential risk factor for type 2 diabetes. At present, there exist several clinical trials and studies on the usage of metformin in the treatment of PCOS patients in prediabetes, and the practical application of metformin in clinical practice has years of history. The treatment plan of metformin is of great significance in preventing type 2 diabetes in PCOS patients and assisting pregnancy in PCOS infertile patients.
Conditions
- Polycystic Ovary Syndrome
- Metformin
Interventions
- DRUG
-
All participants among the three groups were treated with metformin
Sponsors & Collaborators
-
RenJi Hospital
lead OTHER
Principal Investigators
-
Tao Tao, Dr. · RenJi Hospital
Eligibility
- Min Age
- 18 Years
- Max Age
- 45 Years
- Sex
- FEMALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2016-01-01
- Primary Completion
- 2023-01-01
- Completion
- 2023-01-01
Countries
- China
Study Locations
More Related Trials
-
Efficacy of Metformin and Diane-35 on PCOS Patients,a Randomized, Controlled, Prospective Clinical Trial
NCT01573377 ·Status: COMPLETED ·Phase: NA
-
Metformin Administration in Infertile Anovulatory PCOS Patients
NCT00501787 ·Status: WITHDRAWN ·Phase: PHASE4
-
Effects of GLP-1 Analogue Combined With Metformin and Metformin on Gonadal and Metabolic Profiles in Chinese Overweight/Obese PCOS Patients With Hyperandrogenemia.
NCT04969627 ·Status: COMPLETED ·Phase: PHASE4
-
Metformin Treatment in Polycystic Ovary Syndrome (PCOS)
NCT02198417 ·Status: UNKNOWN ·Phase: NA
-
Chiglitazar/Metformin in Non-obese Women With PCOS
NCT06125587 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Metformin Improves Clinical Pregnancy Rate in Polycystic Ovarian Syndrome Patients
NCT02562664 ·Status: COMPLETED ·Phase: PHASE2
-
Impact of Metformin on In Vitro Fertilization Outcomes in Overweight and Obese PCOS Women
NCT02910817 ·Status: COMPLETED ·Phase: NA
-
Metformin in Patients With PCOS and Predictors of Poor Ovarian Response Ongoing In-vitro Fertilization
NCT01208740 ·Status: TERMINATED ·Phase: PHASE4
-
Study to Assess the Effect of Metformin Supplementation on IVF Outcome in Patients With Polycystic Ovarian Syndrome.
NCT03086005 ·Status: COMPLETED ·Phase: PHASE3
-
Effects of Metformin and Oral Hormonal Contraceptive in Adolescents With Polycystic Ovary Syndrome
NCT00988078 ·Status: UNKNOWN ·Phase: NA
-
Metformine and CC Compared With Placebo and CC for Induction Ovulation in PCOS Patients With Insulin Resistant
NCT02523898 ·Status: TERMINATED ·Phase: PHASE2
-
Study of Acupuncture to Control Weight and Improve Pregnancy Rates in Overweight/Obese PCOS Patients
NCT06717087 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Effect of Dosage of Metformin on Menstruation and Lipid Profile in Women With Polycystic Ovary Syndrome
NCT01474967 ·Status: COMPLETED ·Phase: NA
-
The Effect of Metformin on Different Hormones in PCOS Patients
NCT02568488 ·Status: COMPLETED ·Phase: PHASE4
-
SGLT2 Inhibitors in Patients With PCOS
NCT04700839 ·Status: COMPLETED ·Phase: PHASE4
-
Effects of Pioglitazone Combined With Metformin on Gonadal and Metabolic Profiles in Chinese Nonobese PCOS Patients.
NCT05519813 ·Status: UNKNOWN ·Phase: PHASE4
-
Endometrial Effects of Metformin Action in Women With Polycystic Ovarian Syndrome (PCOS)
NCT01070160 ·Status: COMPLETED
-
Metformin Treatment Before in Vitro Fertilization (IVF) in Women With Ultrasound Evidence of Polycystic Ovaries
NCT01046032 ·Status: COMPLETED ·Phase: NA
-
The Effects of OCP and Metformin on Clinical, Hormonal, Metabolic and Ultrasonographic Characteristics in PCOS
NCT02866786 ·Status: COMPLETED ·Phase: PHASE4
-
Metformin and Lifestyle Intervention in Women With Polycystic Ovary Syndrome
NCT00679679 ·Status: COMPLETED ·Phase: PHASE4
-
Metformin and Folate Supplementation in Polycystic Ovary Syndrome (PCOS) Patients
NCT00953355 ·Status: COMPLETED ·Phase: PHASE4
-
CANA/Met in Non-diabetic Women With PCOS
NCT04973891 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
The Effect of GLP-1 Agonists Versus OCs on Reproductive Disorders and Cardiovascular Risks in Overweight PCOS
NCT03151005 ·Status: COMPLETED ·Phase: PHASE4
-
Effect of Metabolic Surgery on Live Birth Rate of Offspring in Obesity Polycystic Ovarian Syndrome Patients
NCT04151459 ·Status: UNKNOWN ·Phase: NA
-
Treating Obese PCOS Patients With LSG vs. Met
NCT04508634 ·Status: UNKNOWN ·Phase: PHASE4