Cerebrospinal Fluid Proteome in Hydrocephalus
NCT02016352 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 100
Last updated 2025-12-15
Summary
PROLIPHYC is a collaborative prospective study that aims at discovering deep cerebrospinal fluid (CSF) proteome with a new clinically-compatible proteomics strategy, in a cohort of 100 patients suspected of neurodegenerative diseases and/or normal pressure hydrocephalus.
Conditions
- Normal Pressure Hydrocephalus
Interventions
- BIOLOGICAL
-
patient CSF extraction with hydrocephalus
CSF extraction
- BIOLOGICAL
-
witness CSF extraction
CSF extraction from patient not suffering from hydrocephalus
Sponsors & Collaborators
-
University Hospital, Toulouse
lead OTHER
Principal Investigators
-
Eric SCHMIDT, MD PhD · University Hospital, Toulouse
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- OTHER
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2013-03-31
- Primary Completion
- 2015-09-30
- Completion
- 2015-12-31
Countries
- France
Study Locations
More Related Trials
-
Establishing the Physiology of Syringomyelia
NCT00001327 ·Status: COMPLETED
-
Vascular Risk Factors in INPH-patients
NCT01850914 ·Status: COMPLETED
-
NIMIP: Non Invasive Measurement of the Intracranial Pressure
NCT01685450 ·Status: UNKNOWN ·Phase: PHASE4
-
Computerised Testing of Cognitive Response to Cerebrospinal Fluid Shunting in Idiopathic Normal Pressure Hydrocephalus
NCT01618500 ·Status: UNKNOWN
-
Clinical Significance and Prognostic Value of Prenatal Diagnosis of Obliteration of the Cavum Septum Pellucidum
NCT06782802 ·Status: RECRUITING
-
Analysis of Disturbances in Neurofluid Dynamics in Type I Chiari Malformations
NCT06502431 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Development of a Patient-reported Outcome Measure for Chiari Malformation and Syringomyelia
NCT06011226 ·Status: NOT_YET_RECRUITING
-
The Freiburg Registry on SpontanEous IntercrAnial Hypotension (SIH) & Post-duraL Puncture Headache (PDPH)
NCT06711731 ·Status: RECRUITING
-
Perioperative CSF Leak Management - an Opinion Study
NCT04124523 ·Status: COMPLETED
-
ICP & Outflow Study
NCT06436820 ·Status: NOT_YET_RECRUITING
-
Prediction Model of Improvement of Disturbance of Consciousness in Patients With Hydrocephalus After Shunt Operation
NCT05237102 ·Status: UNKNOWN ·Phase: NA
-
Computerized Neuropsychology in Idiopathic Normal Pressure Hydrocephalus (INPH)
NCT01265251 ·Status: COMPLETED
-
Cerebrospinal Fluid IL-6, IL-8 and PCT as Early Marker of an Intrathecal Infection in Neurosurgical Patients
NCT02875808 ·Status: COMPLETED
-
Dynamic Measurement of Cerebrospinal Fluid in Healthy Subjects: Pilot Study
NCT06743347 ·Status: COMPLETED ·Phase: NA
-
Assessment of CSF Shunt Flow During Activities of Daily Living and Sleep With a Thermal Measurement Device
NCT07050628 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Prevalence of Trephined Syndrome After Decompressive Craniectomy
NCT03186157 ·Status: TERMINATED
-
Comparison of Continuous Noninvasive and Invasive Intracranial Pressure Measurement--Celda Infusion Subprotocol
NCT01976559 ·Status: COMPLETED ·Phase: NA
-
Natural History of Cerebral Palsy Prospective Study
NCT05576948 ·Status: RECRUITING
-
The Role of CSF in Chiari II Brain Malformation
NCT06560788 ·Status: NOT_YET_RECRUITING
-
BRAIN-HEART Ultrasound Study Normative Values for Transcranial Doppler Based Cerebral Blood Flow Assessment
NCT05924503 ·Status: TERMINATED
-
Brain Skull Deformation as a Non-invasive Intracranial Pressure (ICP) Measure
NCT05121155 ·Status: COMPLETED
-
Efficacy Study of Hydrocephalus Surgery by Methods of Neuroelectrophysiology
NCT04363658 ·Status: UNKNOWN
-
Posterior Fossa Intracranial Pressure (ICP) Measurement: Clinical Study
NCT04675216 ·Status: RECRUITING
-
Collection of Cerebrospinal Fluid in Healthy Children
NCT01698229 ·Status: TERMINATED
-
Effect of Acetazolamide & Position in CSF Leakage and Collection and Wound Dehiscence
NCT01867268 ·Status: UNKNOWN ·Phase: PHASE2